LABORATORY FOR HEALTH, OMICS AND PATHWAY EXPLORATION

Scientific still life showing microbial research, a pipette and petri dish

MICROBIAL BIOCHEMISTRYMOLECULAR FUNCTIONONE HEALTHSUSTAINABLE BIOTECH

Life is a network
of pathways

HOPE Lab is a microbial biochemistry and One Health research laboratory in the Department of Biochemistry and Molecular Biology at the University of Chittagong, Bangladesh. It explores microbial biochemical pathways, molecular mechanisms and functional biomolecules, and how they shape biological interactions that influence host health and ecosystem functioning. Combining experimental biochemistry and microbiology with genomics, glycomics, metabolomics and bioinformatics, HOPE Lab investigates questions relevant to One Health, food systems and environmental biotechnology.

Research across molecules, organisms and systems

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Fermented foods and microbial research

Functional Foods and Probiotics

We study fermented foods, probiotic microorganisms, and their health-promoting molecules to inform the development of functional foods, with emphasis on food quality, safety, nutritional value, and public health.

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Molecular structures and biological activity

Molecular Diversity and Bioactivity

Our research explores the diversity of microbial products including natural pigments, exopolysaccharides, enzymes, and other bioactive compounds with potential health and biotechnological applications.

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Biological systems and molecular networks

Systems Biology

We combine genomics, glycomics, metabolomics, and bioinformatics to investigate molecular characteristics and biological processes in bacteria and fungi.

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Ecological interactions and environmental contexts

Ecology and Environmental Interactions

We explore how microorganisms adapt to and interact with hosts, plants, and changing environments, including fermented foods, plant-associated communities, extreme habitats, and polluted environments.

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THE HOPE LAB RESEARCH FRAMEWORK

A One Health Approach

The 1H → 2O → 3P → 4E framework organizes our research across four complementary dimensions, spanning One Health, molecular investigations, biological pathways, ecological interactions, and environmental sustainability.

1H

One Health

Interconnected Health Systems

Understanding biological factors connecting human, animal, plant, and environmental health.

2O

Organisms · Omics

Molecular investigation

Investigating organisms and their molecular profiles using genomics, glycomics, and metabolomics.

3P

Pathways · Probiotics · Protection

Biological functions

Exploring microbial products, biochemical pathways, and their potential applications.

4E

Ecology · Environment · Evolution · Emergence

Ecological interactions and sustainability

Understanding ecology, adaptation, and function in different environments.

RESEARCH OUTPUT

Publications and Contributions

23

Peer-Reviewed Papers

Explore 23 peer-reviewed papers and an additional accepted manuscript across microbial biochemistry, probiotics, functional biomolecules, genomics, glycobiology, and environmental biotechnology.

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Selected research contributions from HOPE Lab members and collaborators.

RECENT PUBLICATIONSSELECTED / 2026
2026

Multifunctional lactic acid bacteria from sugarcane juice with probiotic properties for gut adaptation, health benefits, food preservation and quality enhancement

Scientific Reports

DOI: 10.1038/s41598-026-40844-5

2026

Comparative evaluation of different sol–gel processed M-type barium hexaferrite on structural and antimicrobial efficacy

Next Bioengineering

DOI: 10.1016/j.nxbio.2026.100047

2026

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N-glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal

DOI: 10.1111/febs.70666

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FOUNDER & PRINCIPAL INVESTIGATOR

Dr. Tanim Jabid Hossain

Associate Professor · Department of Biochemistry and Molecular Biology, University of Chittagong

Dr. Tanim Jabid Hossain is a microbial biochemist whose research spans microbial metabolism, glycobiology and functional biomolecules. From 2012 to 2015, he pursued doctoral research through the RIKEN–Saitama University Joint Program in Japan while serving as an International Program Associate with RIKEN's Glycometabolome Team. At HOPE Lab, he directs research on microbial biochemical pathways, probiotics and bioactive molecules, examining their functions and interactions in contexts relevant to One Health.

Meet the lab team

CONNECT THROUGH RESEARCH

Scientific questions grow through collaboration.

Many biological processes, including those involving microorganisms and their interactions with hosts and environments, remain to be understood at the molecular and ecological levels. Through biochemical and molecular research, HOPE Lab investigates these processes and explores how new insights may contribute to health, biotechnology and sustainable solutions. We welcome scientific discussions and collaborations that bring different perspectives together to advance biological understanding and explore new possibilities.

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